Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Apr 24, 2026

Cell Capture Using a Microfluidic Device
29:02

Cell Capture Using a Microfluidic Device

Published on: October 1, 2007

5.0K

Computational fluid dynamics-based design of a microfabricated cell capture device.

Gabor Jarvas1, Marton Szigeti2, Laszlo Hajba3

  • 1MTA-PE Translational Glycomics Research Group, University of Pannonia, Veszprem, Hungary CEITEC-Central European Institute of Technology, Brno, Czech Republic.

Journal of Chromatographic Science
|September 11, 2014
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improvement of Peak Integration in Capillary Electrophoresis: Reference Data Set No. 1.

Electrophoresis·2026
Same author

Fluorescent properties of FDA-approved anti-leukemia drugs.

Biomedical optics express·2026
Same author

Analysis of Soft Tissue N-Glycome Profiles in Oral Squamous Cell Carcinoma, a Pilot Study.

International journal of molecular sciences·2026
Same author

Capillary Gradient Gel Electrophoresis.

Gels (Basel, Switzerland)·2026
Same author

Nanoindentation Analysis of SU-8 Coated Wafers at Different Baking Phases.

Polymers·2025
Same author

Absence of Hofmeister Selectivity in Hydrophobic Ion-Exchanger Nanopores.

Analytical chemistry·2025

This study presents a novel microfluidic cell capture device, optimized using computational fluid dynamics (CFD) simulations and validated experimentally. The compact bioanalytical system utilizes micropillars for efficient cell capture.

Area of Science:

  • Biomedical Engineering
  • Microfluidics
  • Bioanalytical Systems

Background:

  • Developing compact and integrated bioanalytical systems is crucial for efficient cell capture.
  • Microfluidic devices offer a promising platform for cell manipulation and analysis.

Purpose of the Study:

  • To design, fabricate, and validate a novel microfluidic cell capture device.
  • To leverage computational fluid dynamics (CFD) for optimizing microfluidic device design.
  • To create a compact, integrated bioanalytical system for cell capture.

Main Methods:

  • Device design and optimization using computational fluid dynamics (CFD) simulations.
  • Rapid prototyping of microdevices using poly-dimethylsiloxane (PDMS) via soft lithography.
  • Experimental validation of CFD models through yeast cell trajectory tracing and microscopic recording.

More Related Videos

A Microfluidic Technique to Probe Cell Deformability
09:47

A Microfluidic Technique to Probe Cell Deformability

Published on: September 3, 2014

10.9K
A Microfluidic Device with Groove Patterns for Studying Cellular Behavior
13:50

A Microfluidic Device with Groove Patterns for Studying Cellular Behavior

Published on: August 30, 2007

12.0K

Related Experiment Videos

Last Updated: Apr 24, 2026

Cell Capture Using a Microfluidic Device
29:02

Cell Capture Using a Microfluidic Device

Published on: October 1, 2007

5.0K
A Microfluidic Technique to Probe Cell Deformability
09:47

A Microfluidic Technique to Probe Cell Deformability

Published on: September 3, 2014

10.9K
A Microfluidic Device with Groove Patterns for Studying Cellular Behavior
13:50

A Microfluidic Device with Groove Patterns for Studying Cellular Behavior

Published on: August 30, 2007

12.0K

Main Results:

  • Successful design and fabrication of a microfluidic cell capture device with internal micropillars.
  • CFD simulations accurately predicted device performance.
  • Experimental validation confirmed the numerical model's accuracy in predicting flow characteristics.

Conclusions:

  • The developed microfluidic cell capture device is a compact and integrated bioanalytical system.
  • CFD modeling is a valuable tool for the early-stage development of microfluidic cell capture devices.
  • This approach facilitates efficient cell capture and analysis.