Related Experiment Video
Updated: Apr 24, 2026

11:56
A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells
Published on: April 11, 2014
12.7K
Scurvy extinct? Think again!
Vela D Desai1, Shweta Hegde2, Durgesh N Bailoor3
1Associate Professor, Department of Oral Medicine and Radiology, Jaipur Dental College, Jaipur, Rajasthan, India.
International Journal of Clinical Pediatric Dentistry
|September 11, 2014
Summary
Scurvy, a vitamin C deficiency disease, is rare in children but still occurs. Prompt diagnosis and vitamin C treatment led to rapid recovery in a 6-year-old boy.
Area of Science:
- Nutrition and Dietetics
- Pediatric Medicine
- Clinical Case Studies
Background:
- Scurvy, a disease caused by vitamin C deficiency, is infrequently diagnosed in pediatric patients despite its sporadic occurrence in developed nations.
- Vitamin C deficiency can result from inadequate dietary intake or impaired absorption, leading to scurvy.
- This condition, though uncommon, warrants consideration in pediatric cases presenting with suggestive symptoms.
Observation:
- A 6-year-old boy presented with classic scurvy symptoms including bleeding gums, musculoskeletal pain, and general weakness.
- Initial laboratory investigations, including hemoglobin and total blood count, were performed.
- The patient's condition showed remarkable improvement within four days of initiating oral vitamin C supplementation.
Findings:
- The clinical presentation, laboratory results, and rapid positive response to ascorbic acid confirmed the diagnosis of scurvy.
- This case highlights that scurvy is not extinct and can manifest in children.
- Effective treatment involves timely vitamin C supplementation.
Implications:
- Oral and general physicians must maintain a high index of suspicion for scurvy in pediatric patients with relevant symptoms.
- Early recognition and intervention are crucial for successful treatment and recovery.
- This case underscores the importance of considering nutritional deficiencies in differential diagnoses.
Related Concept Videos
Vitamins
2.6K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
2.6K
Cirrhosis II: Pathophysiology
26
Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to...
26
Cancer Prevention
6.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.5K

