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Author Spotlight: Exploring Acupuncture in Alzheimer's Research from Thread-Embedding Techniques to Clinical Trials
Published on: May 10, 2024
Pre-moxibustion and moxibustion prevent Alzheimer's disease
Yanjun Du1, Ruolan Liu2, Guojie Sun1
1College of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430061, Hubei Province, China.
Abstract:
The Alzheimer's disease model in Wistar rats was established by injection of amyloid β-peptide (Aβ1-42) into the hippocampal CA1 region. Rats were treated with suspended moxibustion on Baihui (GV20) and Shenshu (BL23) acupoints. Prior to and post Aβ1-42 exposure. Results showed no evidence of apoptosis in hippocampal neurons, a significantly reduced apoptosis rate of neurons and improved learning and memory abilities were observed in the Alzheimer's disease model. In particular, moxibustion prior to Aβ1-42 exposure was more effective than moxibustion after Aβ1-42 exposure in protecting the neuronal structure and lowering the apoptosis rate. Our findings indicate that a combination of preventive and therapeutic moxibustion has a beneficial effect for the prevention of Alzheimer's disease development.
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