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Related Experiment Video

Updated: Apr 24, 2026

$Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing$

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

Open-access optical microcavities for lab-on-a-chip refractive index sensing.

A A P Trichet¹, J Foster, N E Omori

¹Department of Materials, University of Oxford, OX1 3PH, UK. aurelien.trichet@materials.ox.ac.uk.

|September 11, 2014

Summary

Open-access optical microcavities enable label-free sensing on a chip. This technology achieves high sensitivity for detecting minute changes in refractive index, crucial for biosensing applications.

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Last Updated: Apr 24, 2026

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Area of Science:

Optofluidics
Nanophotonics
Biosensing

Background:

Open-access optical microcavities offer a novel platform for lab-on-a-chip sensing.
These devices provide access to confined electromagnetic fields and femtoliter detection volumes.

Purpose of the Study:

To characterize open-access optical microcavities for refractive index sensing.
To demonstrate noise reduction techniques for enhanced sensing accuracy.

Main Methods:

Simultaneous tracking of resonances across an array of microcavities.
Refractive index sensing using optical microcavity shifts.

Main Results:

Ambient noise in refractive index data was significantly reduced.
A sensitivity of 3.5 × 10(-4) RIU was achieved.
Detection of 500,000 glucose molecules in aqueous solution was demonstrated.

Conclusions:

Open-access optical microcavities are effective for label-free refractive index sensing.
Noise reduction strategies enhance the performance of optofluidic sensors.
This technology holds promise for sensitive biosensing applications.