Meal-stimulated gastrin release in normal men and women

Due to the importance of possible differences in gastrin and parietal cell secretory functions related to gender, we attempted to determine whether normal men and women release gastrin differently in response to a standard meal. Eight male and 9 female volunteers (mean age 25 and 23 years) ingested a standard meal consisting of 15g of protein, 13g of fat, and 36g of carbohydrates. Plasma for gastrin determination was drawn at baseline and at 5, 10, 15, 20, 30, 40, 60, 90 and 120 minutes after eating. No significant differences were found in basal or meal-stimulated gastrin of males or females.