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Theranostics: A treasured tailor for tomorrow.

S Jeelani1, R C Jagat Reddy2, Thangadurai Maheswaran3

  • 1Department of Oral Medicine and Radiology, Indira Gandhi Institute of Dental Sciences, Puducherry, India.

Journal of Pharmacy & Bioallied Sciences
|September 12, 2014
PubMed
Summary
This summary is machine-generated.

Theranostics combines diagnosis and therapeutics for personalized medicine, ensuring the right drug for the right patient. This approach, utilizing pharmacogenetics and nanomedicine, transitions healthcare to predictive and preventive strategies.

Keywords:
Diagnosispersonalized medicinetheranosticstherapy

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Area of Science:

  • Biomedical Sciences
  • Pharmacology
  • Nanotechnology

Background:

  • Theranostics represents a paradigm shift from conventional medicine towards patient-centered, personalized care.
  • It integrates diagnostic and therapeutic strategies to optimize treatment efficacy and safety.
  • The approach is crucial for advancing precision medicine, tailoring treatments to individual patient profiles.

Purpose of the Study:

  • To highlight the principles and significance of theranostics in modern pharmacotherapy.
  • To emphasize the role of genetics, proteomics, and biomarker profiling in theranostic applications.
  • To explore the application of nanomedicine within theranostics, particularly in oncology.

Main Methods:

  • Review of current literature on theranostics and personalized medicine.
  • Analysis of the integration of diagnostic tools with therapeutic agents.
  • Examination of the role of omics technologies (genomics, proteomics) and nanotechnology in theranostics.

Main Results:

  • Theranostics enables targeted, safe, and efficient drug delivery, improving patient outcomes.
  • Pharmacogenetics, proteomics, and biomarker profiling are foundational to theranostic strategies.
  • Nanomaterials like liposomes, nanoparticles, and quantum dots are vital for advanced theranostic applications, especially in oncology.

Conclusions:

  • Theranostics facilitates a transition from "trial and error" medicine to predictive, preventive, and personalized pharmacotherapy.
  • It offers a cost-effective and successful treatment protocol tailored to individual patient needs.
  • The integration of diagnostics, therapeutics, and advanced technologies like nanomedicine enhances the quality of healthcare.