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Updated: Apr 24, 2026

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
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Supranuclear eye movement disorders.

João Lemos1, Eric Eggenberger

  • 1aDepartment of Neurology, Coimbra University Hospital Center, Coimbra, Portugal bDepartment of Neurology and Ophthalmology, Michigan State University, East Lansing, Michigan, USA.

Current Opinion in Ophthalmology
|September 12, 2014
PubMed
Summary
This summary is machine-generated.

Recent research on supranuclear ocular motor disorders reveals insights into eye movement control and potential new therapies. Advances in imaging and treatments offer hope for visual and vestibular rehabilitation.

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Neurology

Background:

  • Supranuclear ocular motor disorders affect eye movement control.
  • Recent advancements provide new data on these conditions.

Purpose of the Study:

  • To review supranuclear ocular motor disorders.
  • To highlight new data published in the past year.

Main Methods:

  • Review of recent scientific literature.
  • Analysis of anatomic and functional imaging studies.

Main Results:

  • Perceptual adaptation may explain discrepancies between objective saccade measurements and functional visual impairment.
  • Neurodegenerative disorders selectively disrupt different eye movement classes.
  • Deep brain stimulation shows promise for Parkinson's disease pursuit deficits.
  • Subcortical pathways are crucial for infantile esotropia.
  • Vergence-vestibular interactions are better understood in vestibular failure.
  • 4-aminopyridine shows potential for treating nystagmus in ataxia-telangiectasia.

Conclusions:

  • Anatomic and functional imaging offer new insights into ocular motor circuitry.
  • Novel therapies may improve visual and vestibular rehabilitation for affected patients.