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Updated: Apr 24, 2026
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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
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[Potentials for the phytotherapy in patients with chronic pyelonephritis]
Urologiia (Moscow, Russia : 1999)
|September 13, 2014
Summary
This study found that adding the phytodrug prolit super septo to standard antibacterial treatment for chronic pyelonephritis significantly improved patient outcomes and reduced recurrence rates.
Area of Science:
- Nephrology
- Pharmacology
- Urology
Background:
- Chronic pyelonephritis is a serious kidney infection.
- Exacerbations require effective treatment to prevent complications.
Purpose of the Study:
- To evaluate the efficacy of a phytodrug, prolit super septo, as an adjunct to standard antibacterial therapy for chronic pyelonephritis.
- To assess the impact on treatment duration, symptom resolution, and disease recurrence.
Main Methods:
- A randomized controlled trial involving 66 patients with chronic pyelonephritis in exacerbation.
- Study group received standard treatment plus prolit super septo; control group received standard treatment only.
- Outcomes measured included symptom resolution, laboratory parameters, intrarenal blood flow, and 3-month recurrence rates.
Main Results:
- The study group showed higher treatment effectiveness and shorter treatment duration.
- Earlier normalization of leukocyturia, bacteriuria, body temperature, and blood analysis was observed in the study group.
- Intrarenal blood flow restoration was faster in the study group.
- No recurrences were noted in the study group after 3 months, compared to 14% in the control group.
Conclusions:
- Adjunctive therapy with prolit super septo enhances the effectiveness of standard treatment for chronic pyelonephritis.
- This phytodrug appears to reduce treatment time, accelerate recovery, and prevent disease recurrence.
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