Related Experiment Video

Updated: Apr 24, 2026

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain
07:45

Cervical Lymph Duct-Cannulated Rat Model for Assessing Lymphatic Transport from the Head and Brain

Published on: March 10, 2026

170

Pediatric cervical lymphadenopathy

Tara L Rosenberg1, Abby R Nolder1

  • 1Department of Otolaryngology/Head and Neck Surgery, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, 1 Children's Way, Slot 836, Little Rock, AR 72202, USA.

Otolaryngologic Clinics of North America
|September 13, 2014
PubMed

Insights

Evaluating pediatric cervical lymphadenopathy requires a thorough history and physical exam. While infections are common, consider neoplasms and use ultrasound judiciously for diagnosis and management.

Area of Science:

  • Pediatric Medicine
  • Otolaryngology
  • Diagnostic Imaging

Background:

  • Cervical lymphadenopathy is common in children.
  • Infectious causes are more prevalent than in adults.
  • Neoplastic causes must also be considered.

Purpose of the Study:

  • To provide an overview of the evaluation and management of pediatric cervical lymphadenopathy.
  • To review common and uncommon infectious causes.
  • To discuss indications for surgical intervention.

Main Methods:

  • Review of pertinent literature.
  • Emphasis on thorough history and physical examination.
  • Discussion of the role of imaging, particularly ultrasound.

Main Results:

  • Infectious etiologies are most common in pediatric cervical lymphadenopathy.
  • Neoplasms are less common but important to consider.
  • Ultrasound aids in differentiating causes and guiding management.

Conclusions:

  • A systematic approach including history, physical exam, and judicious imaging is essential.
  • Infections are the primary cause, but malignancy must be ruled out.
  • Surgery is occasionally needed for diagnosis or treatment of infections, rarely for malignancy.

Keywords:
Cervical lymphadenopathyDifferential diagnosisInfectiousNeck massPediatric

More Related Videos

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

13.8K
Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue07:38

Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue

Published on: June 14, 2020

6.9K

Related Concept Videos

Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
13.3K
Development of the Lymphatic System01:15

Development of the Lymphatic System

The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
2.8K
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
7.2K
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
179
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
9.5K
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
89