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Additive manufacturing: From implants to organs.

Tania S Douglas1

  • 1Deputy Dean for Research, Faculty of Health Sciences, University of Cape Town, South Africa. tania.douglas@uct.ac.za.

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
|September 13, 2014
PubMed
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Additive manufacturing (AM), including 3D printing, creates customized products layer by layer. While successful for implants and surgical models, printing functional tissues and organs remains a future goal with transformative potential.

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Manufacturing Technology

Background:

  • Additive manufacturing (AM) builds 3D objects from digital models using layer-by-layer fabrication.
  • 3D printing is a prominent example of AM technology.
  • AM enables high geometric flexibility, facilitating customization for specific applications.

Purpose of the Study:

  • To review the current applications and future potential of additive manufacturing in medicine.
  • To highlight the successes and challenges in using AM for creating biological constructs.

Main Methods:

  • Review of existing literature on additive manufacturing applications in healthcare.
  • Analysis of clinical successes and research frontiers in 3D printing for medical purposes.

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Main Results:

  • AM has demonstrated clinical success in producing surgical planning models, implants, and assistive devices.
  • Scaffold-based tissue engineering utilizes AM for creating complex structures.
  • The fabrication of functional, nature-mimicking tissues and organs via AM is still an ongoing research challenge.

Conclusions:

  • Additive manufacturing offers significant potential for personalized medicine, drug development, and disease research.
  • While current applications are impactful, the ultimate goal of printing complex organs remains a long-term objective.