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Related Concept Videos

Obesity01:24

Obesity

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

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Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
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Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

319
Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
319
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
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Multidisciplinary Approach to Obesity Management: A Case Report
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Obesity in obstetrics.

Salzer Liat1, Luis Cabero2, Moshe Hod1

  • 1Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|September 13, 2014
PubMed
Summary
This summary is machine-generated.

Maternal obesity during pregnancy elevates risks for mothers and babies. Preconception, prenatal, and postnatal nutritional and exercise guidance are crucial for managing risks and promoting healthy weight loss.

Keywords:
noncommunicative diseaseobesityobstetric complicationsoverweight

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Area of Science:

  • Obstetrics and Gynecology
  • Public Health
  • Reproductive Medicine

Background:

  • Obesity is a significant global health concern with increasing prevalence.
  • Pregnancy in obese women presents elevated risks for both maternal and fetal health.
  • Obesity during pregnancy is linked to comorbidities like diabetes and hypertension, further increasing risks.

Purpose of the Study:

  • To highlight the challenges in obstetric care related to maternal obesity.
  • To emphasize the importance of preconception, prenatal, and postnatal interventions.
  • To underscore the long-term health implications for offspring.

Main Methods:

  • This study is a review of current literature on maternal obesity.
  • It synthesizes information on risks, comorbidities, and management strategies.
  • Focuses on the cycle of obesity from mother to child.

Main Results:

  • Maternal obesity is inversely correlated with the severity of obesity, indicating higher risks with greater severity.
  • Associated comorbidities significantly amplify maternal and fetal risks.
  • Maternal obesity contributes to a cycle of obesity and noncommunicable diseases in offspring.

Conclusions:

  • Comprehensive preconception, prenatal, and postnatal care, including nutritional and exercise guidance, is essential.
  • Effective management can mitigate risks associated with maternal obesity.
  • Addressing maternal obesity is critical for breaking the intergenerational cycle of obesity and related diseases.