Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

2.2K
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
2.2K
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

2.0K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expanding the reach of a fall prevention intervention for older adult emergency department patients through telehealth: a trial protocol.

Frontiers in public health·2026
Same author

Blood pro-thrombotic analytes and platelet activation are associated with post-acute sequelae of COVID-19.

BMC infectious diseases·2025
Same author

Remote monitoring of bone healing via bending with direct electromagnetic coupling sensing in an exploratory tibial fracture study.

Injury·2025
Same author

Ophthalmic anaesthesia: a declining skill in anaesthetic training?

Eye (London, England)·2025
Same author

Assessing the environmental impact of propofol use in anaesthesia: a call for surveillance monitoring.

British journal of anaesthesia·2025
Same author

Prognostic significance of subcarinal lymph node involvement in patients with Siewert type I and II gastro-esophageal junctional adenocarcinoma: an analysis of 698 patients undergoing Ivor-Lewis esophagectomy.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2025

Related Experiment Video

Updated: Apr 24, 2026

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

2.7K

Breast surgery using thoracic paravertebral blockade and sedation alone.

James Simpson1, Arun Ariyarathenam2, Julie Dunn2

  • 1Department of Anaesthesia, South Devon Healthcare NHS Foundation Trust, Torbay Hospital, Lowes Bridge, Torquay TQ2 7AA, UK ; Department of Anaesthesia, Royal Devon & Exeter NHS Foundation Trust, Barrack Road, Exeter EX2 5DW, UK.

Anesthesiology Research and Practice
|September 13, 2014
PubMed
Summary

Thoracic paravertebral block (TPVB) with sedation offers effective anesthesia for breast surgery, particularly for patients who cannot undergo general anesthesia (GA). This ultrasound-guided technique provides a reliable alternative when GA is contraindicated or undesirable.

More Related Videos

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
03:22

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

2.3K
Prone Lateral Minimally Invasive Retropleural Corpectomy Using a Rotatable Radiolucent Jackson Table
04:57

Prone Lateral Minimally Invasive Retropleural Corpectomy Using a Rotatable Radiolucent Jackson Table

Published on: July 3, 2025

1.1K

Related Experiment Videos

Last Updated: Apr 24, 2026

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

2.7K
Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
03:22

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

2.3K
Prone Lateral Minimally Invasive Retropleural Corpectomy Using a Rotatable Radiolucent Jackson Table
04:57

Prone Lateral Minimally Invasive Retropleural Corpectomy Using a Rotatable Radiolucent Jackson Table

Published on: July 3, 2025

1.1K

Area of Science:

  • Anesthesiology
  • Surgical Oncology
  • Regional Anesthesia

Background:

  • Thoracic paravertebral block (TPVB) combined with general anesthesia (GA) is standard for breast surgery analgesia.
  • GA may be contraindicated or undesirable for certain patient populations.
  • Alternative anesthetic techniques are needed for breast cancer surgery.

Purpose of the Study:

  • To evaluate the efficacy and safety of TPVB with conscious sedation as a sole anesthetic for breast cancer surgery.
  • To assess the feasibility of this technique in patients with comorbidities or contraindications to GA.

Main Methods:

  • Twenty-eight patients underwent ultrasound-guided TPVB with propofol or remifentanil-based conscious sedation.
  • TPVB was performed at one to three thoracic levels using local anesthetic.
  • Surgeon-administered local infiltration analgesia was used as needed for top-up.

Main Results:

  • The majority of patients were elderly with significant comorbidities.
  • TPVB at a single thoracic level was sufficient for 54% of patients.
  • Fourteen percent required local infiltration top-ups, and 21% needed rescue opioid analgesia.

Conclusions:

  • Ultrasound-guided TPVB with conscious sedation is an effective and reliable anesthetic for breast surgery.
  • This technique is a valuable option for patients for whom GA is undesirable or poses high risks.