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Updated: Apr 24, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Advances in percutaneous coronary interventions for elderly patients
Jorge A Brenes-Salazar1, Daniel E Forman
1Saint Mary's Hospital, Mayo Clinic, Rochester, MN 55901, USA.
Percutaneous coronary interventions (PCI) benefit older adults with coronary heart disease (CHD), despite higher complication risks. Evidence supports PCI in elderly patients, guiding treatment decisions for this growing population.
Area of Science:
- Cardiology
- Geriatric Medicine
- Interventional Cardiology
Background:
- Coronary heart disease (CHD) is a major cause of death in older adults.
- Elderly patients are often excluded from cardiovascular trials, complicating treatment decisions.
- Managing CHD in the elderly is challenging due to comorbidities and aging.
Purpose of the Study:
- To review current evidence on percutaneous coronary interventions (PCI) in older adults with stable and unstable CHD.
- To compare different PCI strategies and stent types in the elderly population.
- To discuss adjuvant therapies for elderly patients undergoing PCI.
Main Methods:
- Review of existing clinical trials and registry data on PCI in older adults.
- Comparison of outcomes based on stent type (drug-eluting vs. bare-metal).
- Analysis of procedural access routes (transfemoral vs. transradial) and revascularization methods.
Main Results:
- Elderly patients may derive significant benefit from PCI, sometimes exceeding that of younger patients.
- Older adults experience a higher rate of overall complications following PCI.
- Evidence supports the use of PCI in elderly patients with CHD, with careful consideration of risks and benefits.
Conclusions:
- PCI is increasingly utilized in older adults with CHD, demonstrating potential benefits.
- Careful patient selection and management are crucial to mitigate higher complication rates in the elderly.
- Further research is needed to optimize PCI strategies for the aging population with CHD.
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