Is Mitral Annular Calcification Associated With Atherosclerotic Risk Factors and Severity and Complexity of Coronary

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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

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Hemal Bhatt1, Dharmesh Sanghani2, Kell Julliard2

  • 1Department of Internal Medicine, Lutheran Medical Center, Brooklyn, NY, USA cardiothorax@gmail.com.

Angiology
|September 14, 2014
PubMed

Insights

Mitral annular calcification (MAC) is linked to aging and female gender, not coronary artery disease severity. This finding suggests MAC is a benign indicator of age-related heart changes.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Geriatric Cardiology

Background:

  • Mitral annular calcification (MAC) is a common finding in older adults.
  • Its association with coronary artery disease (CAD) requires further clarification.

Purpose of the Study:

  • To investigate the relationship between mitral annular calcification (MAC) and atherosclerotic risk factors.
  • To determine if MAC is associated with the severity and complexity of coronary artery disease (CAD).

Main Methods:

  • Retrospective review of cardiac catheterization reports and electronic medical records (2010-2011).
  • Analysis of 481 patients, categorized into MAC present (209) and MAC absent (272) groups.
  • Inclusion of cardiovascular risk factors, comorbidities, and coronary lesion characteristics.

Main Results:

  • Age and female gender were independent predictors of MAC.
  • MAC was not independently associated with >70% coronary stenosis, number of obstructive vessels, 50%-70% stenosis, or SYNTAX score.
  • Linear regression analysis revealed no significant correlation between MAC and CAD severity or complexity.

Conclusions:

  • Mitral annular calcification appears to be a benign marker of age-related degenerative changes.
  • MAC is likely independent of the severity and complexity of coronary artery disease.

Keywords:
SYNTAX scorecardiovascular risk factorsmitral annular calcification

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