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Ocular anterior segment changes in pregnancy.

Yakov Goldich1, Michael Cooper1, Yaniv Barkana1

  • 1From the Department of Ophthalmology (Goldich, Cooper, Barkana, Avni, Zadok) and the Department of Obstetrics & Gynaecology (Tovbin, Ovadia), Assaf Harofeh Medical Center, Zerifin, Israel; the Department of Ophthalmology (Goldich), Toronto Western Hospital, Ontario, Canada.

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Summary
This summary is machine-generated.

Pregnancy is linked to a steeper cornea and lower intraocular pressure (IOP). These changes in ocular parameters during pregnancy warrant further investigation into corneal biomechanics.

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Area of Science:

  • Ophthalmology
  • Corneal Physiology
  • Ocular Biomechanics

Background:

  • Pregnancy can induce physiological changes throughout the body.
  • The effects of pregnancy on ocular structures, particularly the cornea and intraocular pressure (IOP), are not fully understood.

Purpose of the Study:

  • To investigate alterations in corneal curvature, anterior segment anatomy, and intraocular pressure (IOP) in pregnant women.
  • To compare these ocular parameters between pregnant and nonpregnant women.

Main Methods:

  • A prospective, single-center comparative study was conducted.
  • Ocular Response Analyzer and Pentacam HR Scheimpflug imaging were used to assess anterior eye segments.
  • Data were collected from 60 healthy pregnant women and 60 nonpregnant women.

Main Results:

  • Pregnant women exhibited significantly lower Goldmann-correlated IOP and corneal-compensated IOP compared to nonpregnant women.
  • A statistically significant increase in corneal front steep keratometry (curvature) was observed in the pregnant group.
  • No significant differences were found in corneal hysteresis, corneal resistance factor, posterior corneal curvature, central corneal thickness, anterior chamber depth, or iridocorneal angle.

Conclusions:

  • Pregnancy is associated with increased corneal curvature and decreased intraocular pressure.
  • Further research is needed to determine if these observed changes are due to alterations in corneal biomechanical properties during pregnancy.