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Updated: Apr 24, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Small-changes obesity treatment among veterans: 12-month outcomes
Laura J Damschroder1, Lesley D Lutes2, Susan Kirsh3
1Veterans Affairs Center for Clinical Management Research, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan.
Background:
Weight-loss trials tend to recruit highly selective, non-representative samples. Effective weight-loss approaches are needed for real-world challenging populations.
Purpose:
To test whether a small-changes intervention, delivered in groups or via telephone, promotes greater weight loss than standard obesity treatment in a predominantly male, high-risk Veteran population. Data were collected in 2010-2012 and analyzed in 2013.
Design:
A three-arm, 12-month randomized pragmatic effectiveness trial.
Setting/Participants:
Four-hundred eighty-one overweight/obese participants from two Midwestern Veterans Affairs (VA) Medical Centers were randomly assigned to one of three programs: the 12-month Aspiring to Lifelong Health (ASPIRE) weight-loss program delivered (1) individually over the phone (ASPIRE-Phone) or (2) in-person group sessions (ASPIRE-Group); compared to (3) VA's standard weight-loss program (MOVE!).
Intervention:
Twenty-eight sessions with a non-clinician coach via telephone or in-person groups using a small-changes obesity treatment approach compared to a 15-30-session standard VA program.
Main Outcome Measures:
Twelve-month change in weight (kilograms).
Results:
Participants in all three arms lost significant (p<0.01) weight at 12 months. Participants in the ASPIRE-Group arm lost significantly more weight at 12 months than those in the other two treatment arms (-2.8 kg, 95% CI=-3.8, -1.9, in ASPIRE-Group vs -1.4 kg, 95% CI=-2.4, -0.5, in ASPIRE-Phone and -1.4 kg, 95% CI=-2.3, -0.4) in MOVE!(®). ASPIRE-Group resulted in greater improvements in all other anthropometric measures compared to MOVE! at 12 months (p<0.05) and for all (p<0.05) but waist circumference (p=0.23) compared to ASPIRE-Phone.
Conclusions:
Group-based delivery of the ASPIRE weight management program is more effective than MOVE! and the phone-based version of ASPIRE at promoting sustained weight loss in a predominantly male population with multiple comorbidities. The incremental benefits of group-based ASPIRE over the current MOVE! program could yield significant population-level benefits if implemented on a large scale.
Insights
Group-based weight loss (ASPIRE-Group) significantly outperformed phone-based (ASPIRE-Phone) and standard (MOVE!) programs in a trial with Veterans. This small-changes intervention shows promise for real-world weight management.
Area of Science:
- Obesity research
- Behavioral medicine
- Public health
Background:
- Weight-loss trials often use selective samples, limiting generalizability.
- Challenging, real-world populations require effective weight management strategies.
Purpose of the Study:
- To compare a small-changes intervention (ASPIRE) delivered via phone or group sessions against standard care (MOVE!) in Veterans.
- To assess effectiveness in a predominantly male, high-risk population.
Main Methods:
- A 12-month, three-arm randomized pragmatic effectiveness trial.
- 481 overweight/obese Veterans randomized to ASPIRE-Phone, ASPIRE-Group, or standard MOVE! program.
- Interventions involved 28 coaching sessions (ASPIRE) vs. 15-30 sessions (MOVE!).
Main Results:
- All groups achieved significant weight loss (p<0.01) at 12 months.
- ASPIRE-Group yielded greater weight loss (-2.8 kg) than ASPIRE-Phone (-1.4 kg) and MOVE! (-1.4 kg) (p<0.05).
- ASPIRE-Group also showed superior improvements in other anthropometric measures compared to MOVE! and ASPIRE-Phone.
Conclusions:
- Group-based ASPIRE is more effective for sustained weight loss in this Veteran population.
- The findings suggest potential for significant population-level benefits if group-based ASPIRE is widely implemented.
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