Related Experiment Video
Updated: Apr 24, 2026

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
Published on: January 31, 2014
On the Asymptotic Relative Efficiency of Planned Missingness Designs
Mijke Rhemtulla1, Victoria Savalei2, Todd D Little3
1Programme Group Psychological Methods, Department of Psychology, University of Amsterdam, Weesperplein 4, Room 208, 1018XA, Amsterdam, Netherlands. m.rhemtulla@uva.nl.
Abstract:
In planned missingness (PM) designs, certain data are set a priori to be missing. PM designs can increase validity and reduce cost; however, little is known about the loss of efficiency that accompanies these designs. The present paper compares PM designs to reduced sample (RN) designs that have the same total number of data points concentrated in fewer participants. In 4 studies, we consider models for both observed and latent variables, designs that do or do not include an "X set" of variables with complete data, and a full range of between- and within-set correlation values. All results are obtained using asymptotic relative efficiency formulas, and thus no data are generated; this novel approach allows us to examine whether PM designs have theoretical advantages over RN designs removing the impact of sampling error. Our primary findings are that (a) in manifest variable regression models, estimates of regression coefficients have much lower relative efficiency in PM designs as compared to RN designs, (b) relative efficiency of factor correlation or latent regression coefficient estimates is maximized when the indicators of each latent variable come from different sets, and (c) the addition of an X set improves efficiency in manifest variable regression models only for the parameters that directly involve the X-set variables, but it substantially improves efficiency of most parameters in latent variable models. We conclude that PM designs can be beneficial when the model of interest is a latent variable model; recommendations are made for how to optimize such a design.
More Related Videos
06:55Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
04:35Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
Published on: July 3, 2020
Related Concept Videos
Assumptions of Survival Analysis
Kaplan-Meier Approach
Censoring Survival Data
Comparing the Survival Analysis of Two or More Groups
Study Design in Statistics
Does aspirin reduce the risk of heart attacks? Is one brand of fertilizer more effective at growing roses than another? Is fatigue as dangerous to a driver as the influence of alcohol? Questions like these are answered using randomized experiments with proper...
Expected Frequencies in Goodness-of-Fit Tests