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Updated: Apr 24, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
Vesicoureteral reflux: current management in children
Pedro-Jose Lopez1, Soledad Celis, Francisco Reed
1Department of Pediatric Urology, Exequiel González Cortés Hospital, Santiago, Chile, pejotalopez@yahoo.com.
Insights
Vesicoureteral reflux (VUR) is a common pediatric urology condition. Current management focuses on kidney preservation, incorporating bladder and bowel dynamics alongside historical treatments like surgery and watchful waiting.
Area of Science:
- Pediatric Urology
- Nephrology
- Medical History
Background:
- Vesicoureteral reflux (VUR) has been a recognized condition since the late 19th century.
- Understanding of VUR has evolved from focusing solely on the vesicoureteral junction to encompassing bladder and bowel dynamics.
- Despite evolving knowledge, the core objective remains kidney and renal function preservation.
Purpose of the Study:
- To provide a comprehensive overview of vesicoureteral reflux (VUR) in children.
- To discuss the historical evolution of VUR research and clinical management.
- To detail current management strategies for pediatric VUR.
Main Methods:
- Review of historical and current literature on vesicoureteral reflux (VUR).
- Analysis of the progression of diagnostic and therapeutic approaches.
- Synthesis of information on surgical, endoscopic, medical, and conservative management options.
Main Results:
- Management strategies for VUR have diversified significantly over time.
- Contemporary approaches integrate a holistic view of the urinary system and associated functions.
- A range of treatments are available, from watchful waiting to various surgical interventions.
Conclusions:
- Vesicoureteral reflux (VUR) management has transformed, emphasizing kidney protection.
- Current pediatric VUR care considers complex factors beyond the ureterovesical junction.
- This article aims to cover all facets of this complex pediatric condition and its management.
Abstract:
Vesicoureteral reflux (VUR) is a disorder that has been studied since the early days of pediatric urology. From 1893, when it was first documented in humans by Pozzi, the research and clinical management of VUR has been marked by pendulum swings through the decades. Initially, the vesicoureteral junction was the main subject of study, whereas current practice takes into account the bladder and bowel dynamics. The primary objective, however, is unchanged: preservation of the kidney and its function. Management of the condition has included open surgery, minimally invasive surgery, endoscopic treatment, antibiotic prophylaxis, and watchful waiting. In this article, we will attempt to cover every angle of this complex pathology and its current management in children.
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