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Is Helicobacter Pylori an endogenous source of diethyl phthalate in humans?
Gina M Hilton1, Jane A Hoppin1
1Department of Biological Sciences, North Carolina State University, CB 7633, Raleigh, NC 27695, United States.
Abstract:
Monoethyl phthalate (MEP) is a metabolite used to assess exposure to diethyl phthalate (DEP). Helicobacter Pylori (HP) has been shown to produce DEP in laboratory studies. We used NHANES 1999-2000 data for 1623 adults to investigate whether HP seropositivity was associated with MEP levels. MEP levels were higher in individuals with HP seropositivity (p=0.0237), however the association differed by race. These results suggest that HP may be an endogenous source of DEP in some populations.
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