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[Data analysis for relationship between aging and cardiothoracic ratio based on C-V segmentation algorithm]

Yuanyuan Hou, Yi Liu, Ping Zhou

    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi
    |September 16, 2014
    PubMed

    Insights

    This study investigated how aging affects heart size, measured by the cardiothoracic ratio (CTR). Findings provide age- and gender-specific reference values for CTR, aiding early detection of heart disease.

    Area of Science:

    • Cardiology
    • Medical Imaging
    • Gerontology

    Background:

    • Cardiac enlargement is a key indicator of cardiovascular and heart diseases.
    • The cardiothoracic ratio (CTR) is a standard metric for assessing heart size on chest X-rays.
    • Establishing normative CTR values across different demographics is crucial for accurate diagnosis.

    Purpose of the Study:

    • To investigate the relationship between aging and the cardiothoracic ratio (CTR).
    • To develop an automated method for calculating CTR from X-ray images.
    • To establish age- and gender-specific reference values for CTR in a working population.

    Main Methods:

    • An improved C-V level set method was developed for automated lung tissue segmentation on X-ray images.
    • The segmentation method enabled automatic computation of the cardiothoracic ratio (CTR).
    • Over 3,120 chest radiographs from Beijing's working population were analyzed to study CTR variations.

    Main Results:

    • The study systematically analyzed the effects of age and gender on CTR.
    • Reference values for CTR were determined for different age and gender groups.
    • The developed C-V level set method demonstrated effectiveness in automated CTR calculation.

    Conclusions:

    • Age and gender significantly influence the cardiothoracic ratio (CTR).
    • The established reference values can aid in quantifying cardiac enlargement.
    • This research supports early identification of potential cardiovascular and heart conditions.

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