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Related Experiment Videos

[Drug-induced pemphigus diseases].

J Civatte

    Dermatologische Monatschrift
    |January 1, 1989
    PubMed
    Summary

    Certain drugs can induce pemphigus, a serious autoimmune condition. D-penicillamine and pyritinol-chlorhydrate are common culprits, but many other medications are also implicated.

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    Persistent acantholytic dermatosis: sex-related differences in clinical presentation?

    Acta dermato-venereologica·1993

    Area of Science:

    • Dermatology
    • Immunology
    • Pharmacology

    Context:

    • Pemphigus is a group of rare autoimmune blistering diseases.
    • Drug-induced pemphigus represents a significant subset of these cases.
    • Identifying causative agents is crucial for patient management.

    Purpose:

    • To provide a comprehensive overview of drugs known to induce pemphigus.
    • To list established and potential drug inducers of pemphigus.
    • To raise awareness among clinicians regarding drug-associated pemphigus.

    Summary:

    • This review details pemphigus diseases triggered by specific medications.
    • Well-documented drug inducers include D-penicillamine and pyritinol-chlorhydrate.
    • Numerous other drugs, such as rifampicin, ibuprofen, and various antibiotics, have been rarely associated with pemphigus induction.

    Impact:

    • Facilitates differential diagnosis of pemphigus by considering medication history.
    • Aids in preventing drug-induced pemphigus through informed prescribing practices.
    • Contributes to a better understanding of drug-induced autoimmunity mechanisms.

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