Related Experiment Video
Updated: Apr 23, 2026

In Situ Immunofluorescent Staining of Autophagy in Muscle Stem Cells
Published on: June 12, 2017
The intriguing regulators of muscle mass in sarcopenia and muscular dystrophy
Kunihiro Sakuma1, Wataru Aoi2, Akihiko Yamaguchi3
1Research Center for Physical Fitness, Sports and Health, Toyohashi University of Technology , Toyohashi , Japan.
Abstract:
Recent advances in our understanding of the biology of muscle have led to new interest in the pharmacological treatment of muscle wasting. Loss of muscle mass and increased intramuscular fibrosis occur in both sarcopenia and muscular dystrophy. Several regulators (mammalian target of rapamycin, serum response factor, atrogin-1, myostatin, etc.) seem to modulate protein synthesis and degradation or transcription of muscle-specific genes during both sarcopenia and muscular dystrophy. This review provides an overview of the adaptive changes in several regulators of muscle mass in both sarcopenia and muscular dystrophy.
More Related Videos
11:41Real Time and Repeated Measurement of Skeletal Muscle Growth in Individual Live Zebrafish Subjected to Altered Electrical Activity
Published on: June 16, 2022
10:10Preparation and Culture of Myogenic Precursor Cells/Primary Myoblasts from Skeletal Muscle of Adult and Aged Humans
Published on: February 16, 2017
Related Concept Videos
Satellite Stem Cells and Muscular Dystrophy
Master Transcription Regulators
Cross-bridge Cycle
Cells Coordinate Growth and Proliferation
mTOR Signaling and Cancer Progression
The mTOR pathway or the...
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...