Adipose derived stem cells and nerve regeneration
Alessandro Faroni1, Richard Jp Smith1, Adam J Reid2
1Blond McIndoe Laboratories, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.
Abstract:
Injuries to peripheral nerves are common and cause life-changing problems for patients alongside high social and health care costs for society. Current clinical treatment of peripheral nerve injuries predominantly relies on sacrificing a section of nerve from elsewhere in the body to provide a graft at the injury site. Much work has been done to develop a bioengineered nerve graft, precluding sacrifice of a functional nerve. Stem cells are prime candidates as accelerators of regeneration in these nerve grafts. This review examines the potential of adipose-derived stem cells to improve nerve repair assisted by bioengineered nerve grafts.
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