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Published on: February 17, 2023
A small-sized graphene oxide supramolecular assembly for targeted delivery of camptothecin
Ying-Ming Zhang1, Yu Cao, Yang Yang
1Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071, P. R. China. yuliu@nankai.edu.cn.
Abstract:
A small-sized graphene oxide supramolecular assembly was obtained by the inclusion complexation of hyaluronated adamantane with β-cyclodextrin and the π-stacking of graphene oxide with camptothecin, exhibiting an excellent stability in the serum environment and a higher inhibition effect toward malignant cells than a free drug.
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