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[Effects of anesthesia induction with propofol on plasma renin activity and atrial natriuretic factor secretion. A
D Journois1, D Safran, K Laborde
1Hôpital Laënnec, Département d'Anesthésie-Réanimation Necker-Enfants Malades, Laënnec.
Cahiers D'Anesthesiologie
|January 1, 1989
Abstract:
The authors have noted a substantial increase in plasma renin activity, when the patients were induced with propofol (2.5 mg.kg-1). Although a direct or an indirect effect of propofol may be suggested, the design of this study is not helpful in pointing out the responsibility of the drug in the observed effects. Further studies including peripheral vascular resistance measurements should be undertaken.