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Updated: Oct 12, 2026

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
Published on: April 8, 2013
[Function-structural features of cardiac adaptation to static physical loads]
Abstract:
The cardiovascular system of 70 white rats was studied during adaptation to the physical static load by means of functional and morphometric techniques. The physical static loads induced variations of adaptive changes of the myocardium: right ventricle hypertrophy was mainly responsible for the cardiac mass increase in 47.1% of rats; 31.4% of the hearts revealed an equal proportional hypertrophy of both ventricles; the predominants increase of the left ventricle mass was found in 17.2% of the animals; no changes were found in 4.3%. The various adaptive rearrangements of the myocardium led to individual peculiarities of the cardiac rhythm regulation.
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