Related Experiment Video
Updated: Apr 23, 2026
06:36
Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
Published on: March 14, 2025
1.0K
Foreign bodies associated with peri-implantitis human biopsies
Thomas G Wilson1, Pilar Valderrama, Maria Burbano
1Private practice, Periodontics, Dallas, TX.
Journal of Periodontology
|September 17, 2014
Summary
This study found titanium and dental cement fragments in peri-implantitis (inflammation around implants) biopsies. These foreign materials were surrounded by inflammatory cells, suggesting a role in implant disease.
Area of Science:
- Oral pathology
- Biomaterials science
- Dental implantology
Background:
- Peri-implantitis is a significant cause of dental implant failure.
- Understanding the histopathologic features of peri-implantitis is crucial for effective management.
Purpose of the Study:
- To describe the histopathologic findings in soft tissue biopsies from implants with peri-implantitis.
- To identify foreign materials within peri-implantitis lesions.
Main Methods:
- Analysis of 36 human peri-implantitis soft tissue biopsies.
- Utilized light microscopy (LM) and scanning electron microscopy (SEM).
- Energy dispersive x-ray spectrometry (EDS) for foreign material composition analysis.
Main Results:
- Inflammatory lesions showed a mix of subacute and chronic inflammation, often with plasma cells.
- Radiopaque foreign bodies were detected in 34 out of 36 biopsies.
- Predominant foreign materials identified were titanium particles and dental cement, surrounded by inflammatory cells.
Conclusions:
- Foreign materials like titanium and cement are present in peri-implantitis tissues.
- The exact introduction mechanism and role of these materials in peri-implantitis pathogenesis require further investigation.
- Future research should focus on the etiology and pathogenesis of material-associated peri-implantitis.
