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Updated: Apr 23, 2026

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Cerebral sinovenous thrombosis in a patient with transient eosinophilia
Hiroyasu Sano1, Takuya Fukuoka, Hajime Maruyama
1Department of Neurology, Saitama Medical University International Medical Center, Japan.
Abstract:
A 67-year-old man with a history of prostatic hypertrophy developed behavioral anomalies and a fever. At admission, diffusion-weighted brain magnetic resonance imaging (MRI) indicated a high-intensity signal lesion on both sides of the cerebral hemisphere. Immediately after hospitalization, he developed paralysis of the left side of the body. Diffusion-weighted MRI indicated hemorrhagic changes in the right and left parietal lobes and right occipital lobe. Magnetic resonance venography indicated superior sagittal sinus occlusion. The blood test results indicated transient eosinophilia. Cases of thrombosis with idiopathic eosinophilia have been reported, but this is the first known case of cerebral sinus thrombosis with transient eosinophilic leukocytosis.
Insights
This case report details a 67-year-old man with prostatic hypertrophy who experienced behavioral changes and fever, leading to the discovery of cerebral sinus thrombosis with transient eosinophilic leukocytosis.
Area of Science:
- Neurology
- Hematology
- Radiology
Background:
- Prostatic hypertrophy can present with varied symptoms.
- Cerebral sinus thrombosis is a rare but serious neurological condition.
- Eosinophilia can be associated with thrombotic events.
Observation:
- A patient with prostatic hypertrophy developed behavioral anomalies and fever.
- Brain MRI revealed lesions and superior sagittal sinus occlusion.
- The patient presented with left-sided paralysis and transient eosinophilia.
Findings:
- The case demonstrates cerebral sinus thrombosis.
- Transient eosinophilic leukocytosis was observed.
- This is the first reported instance of cerebral sinus thrombosis linked to transient eosinophilic leukocytosis.
Implications:
- Highlights a novel association between cerebral sinus thrombosis and eosinophilia.
- Suggests the need for further investigation into eosinophilia's role in thrombosis.
- Emphasizes the importance of comprehensive diagnostic imaging in neurological presentations.
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