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Skelemin association with αIIbβ3 integrin: a structural model

Vitaliy Gorbatyuk1, Khiem Nguyen, Nataly P Podolnikova

  • 1Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut at Storrs , Storrs, Connecticut 06269, United States.

Biochemistry
|September 17, 2014
PubMed
Summary

This study models how skelemin links integrins to myosin, revealing a mechanism for cell adhesion and migration. This structural insight into focal adhesion development is crucial for understanding cell mechanics.

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