Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Overview of Cell Signaling

Overview of Cell Signaling

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...

Overview of Cell Signaling

Overview of Cell Signaling

Animal and Plant Cell Structure

Animal and Plant Cell Structure

Animal and plant cells not only differ in their structure, function, and mode of nutrition but also in how they reproduce, specialize, and organize into complex structures.
Cell Division
Though both plant and animal cells divide by mitosis (for non-gametic cells) and meiosis (for gametic cells), they differ in the specifics of this process. Unlike animal cells, plant cells lack centrosomes — an organelle responsible for organizing the spindle fibers and segregating the chromosomes during...

Cell Diversity

Cell Diversity

The concept of a cell started with microscopic observations of dead cork tissue by Robert Hooke in 1665. Hooke coined the term "cell" based on the resemblance of the small subdivisions in the cork to the rooms that monks inhabited, called cells. About ten years later, Antonie van Leeuwenhoek became the first person to observe the living and moving cells under a microscope. In the century that followed, the theory that cells represented the basic unit of life developed.
Multicellular...

What is Cell Signaling?

What is Cell Signaling?

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.

What is Cell Signaling?

What is Cell Signaling?

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Monocytic niches escape T cell surveillance and promote Mycobacterium tuberculosis persistence in lymph nodes.

Immunity·2026

Same author

Modulation of Ferroptosis During Early <i>Mycobacterium tuberculosis</i> Infection Contributes to Beijing Lineage Strain SA161 Virulence.

bioRxiv : the preprint server for biology·2026

Same author

Host oxidative stress primes mycobacteria for rapid antibiotic resistance evolution.

Nature communications·2026

Same author

Single-cell profiling reveals that dynamic lung immune responses distinguish protection from susceptibility to tuberculosis.

PLoS pathogens·2026

Same author

High-Resolution Quantification of Two-Way Nanobody Synergy Using Automated Liquid Handling and Computational Modeling.

Bio-protocol·2026

Same author

A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture.

bioRxiv : the preprint server for biology·2026

Search research articles

Related Experiment Video

Updated: Apr 23, 2026

Silicon Microchips for Manipulating Cell-cell Interaction

Silicon Microchips for Manipulating Cell-cell Interaction

Published on: August 30, 2007

Systems cell biology.

Fred D Mast¹, Alexander V Ratushny¹, John D Aitchison²

¹Seattle Biomedical Research Institute, Seattle, WA 98109 Institute for Systems Biology, Seattle, WA 98109.

The Journal of Cell Biology

|September 17, 2014

Summary

This summary is machine-generated.

Systems cell biology uses advanced technology and computational modeling to explore cell dynamics. This integrated approach reveals emergent properties, deepening our fundamental understanding of cellular organization and mechanisms.

More Related Videos

Micro-scale Engineering for Cell Biology

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

Published on: August 6, 2013

Related Experiment Videos

Last Updated: Apr 23, 2026

Silicon Microchips for Manipulating Cell-cell Interaction

Silicon Microchips for Manipulating Cell-cell Interaction

Published on: August 30, 2007

Micro-scale Engineering for Cell Biology

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

Published on: August 6, 2013

Area of Science:

Systems cell biology
Quantitative biology
Computational biology

Background:

Cellular organization and dynamics are critical biological processes.
Understanding these processes requires integrating experimental and computational approaches.

Purpose of the Study:

To explore the dynamic properties of cells using recent technological and modeling advances.
To objectively address unsolved cellular mechanisms through interdisciplinary methods.

Main Methods:

High-throughput experimentation
Quantitative analysis
Computational modeling

Main Results:

Advances in technology and modeling enable exploration of cell dynamics.
Merging technology and computation objectively addresses cellular mechanisms.
Revealed emergent properties in cellular systems.

Conclusions:

Integrated systems cell biology approaches provide a comprehensive understanding of cell biology.
This interdisciplinary field is crucial for uncovering fundamental cellular mechanisms.
Technological and computational synergy drives biological discovery.