Related Experiment Video
Updated: Apr 23, 2026

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Modulation of the gut microbiota by nutrients with prebiotic and probiotic properties
Céline Druart1, Maud Alligier1, Nuria Salazar1
1Université catholique de Louvain, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium.
Abstract:
Experimental data in animals, but also observational studies in humans, suggest that the composition of the gut microbiota differs in obese vs. lean individuals, in patients with vs. without diabetes, or in patients presenting other diseases associated with obesity or nutritional disbalance, such as non-alcoholic fatty liver disease (NAFLD) or cardiovascular diseases. In this review, we describe how changes in the composition and/or activity of the gut microbiota by administration of nutrients with probiotic or prebiotic properties can modulate host gene expression and metabolism and thereby positively influence host adipose tissue development and related metabolic disorders.
More Related Videos
Related Concept Videos
Probiotics
Functions of the Gut Microbiota
Gut-Brain Axis
Microbiota of the Large Intestine
Development of Human Microbiota
Microbiota of the Stomach and Small Intestine

