Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Trihybrid Crosses02:27

Trihybrid Crosses

24.5K
Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal...
24.5K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chronic relapsing aseptic meningoencephalitis in Sjögren's disease and cryoglobulinemia successfully treated with intrathecal dexamethasone: a case-based review.

Rheumatology international·2026
Same author

A Competitive Coevolution-based Cancer Driver Pathway Identification Algorithm for Maximizing Coverage, Mutual Exclusivity, and Subnet Importance.

IEEE transactions on computational biology and bioinformatics·2026
Same author

Essential Proteins Prediction Using Features Synergy Model and GO Pure Centrality.

IEEE transactions on computational biology and bioinformatics·2026
Same author

An IRES-like cis-acting element located within the EV-A71 coding region drives translation independent of the 5'-IRES and modulates viral fitness through regulated binding of viral RNA to 3D polymerase.

Journal of virology·2026
Same author

Dose- and time-dependent cardioprotection of liproxstatin-1 via sequential modulation of ferroptosis pathways after myocardial ischemia-reperfusion.

Molecular and cellular biochemistry·2026
Same author

Differentiating walled-off pancreatic necrosis with no documented pancreatitis from mucinous cystic neoplasms: a multicenter LASSO-based nomogram.

BMC gastroenterology·2026
Same journal

Experimental study on deantigenization and trabecular structure effects on bovine cancellous bone compression.

Bio-medical materials and engineering·2026
Same journal

Effects of dentin extract without demineralization on migration and angiogenic potential of human umbilical vein endothelial cells.

Bio-medical materials and engineering·2026
Same journal

Measurement of thermal expansion coefficient of melanin for photoacoustic technology.

Bio-medical materials and engineering·2026
Same journal

Development of chitosan-selenium nanoparticle modified brushite cement: A potential strategy for improved clinical performance in bone regeneration.

Bio-medical materials and engineering·2026
Same journal

Electrostatic layer-by-layer assembly for fabricating morphology-controlled hydroxyapatite/zirconia composite with enhanced osteogenic performance.

Bio-medical materials and engineering·2026
Same journal

The antitumor activity of bismuth lipophilic nanoparticles (BisBAL NPs) on human glioblastoma is higher than temozolomide.

Bio-medical materials and engineering·2026
See all related articles

Related Experiment Video

Updated: Apr 23, 2026

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
11:54

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Published on: October 20, 2019

8.3K

Haplotyping a single triploid individual based on genetic algorithm.

Jingli Wu1, Xixi Chen1, Xianchen Li1

  • 1Department of Computer Science, Guangxi Normal University, Guilin 541004, China.

Bio-Medical Materials and Engineering
|September 18, 2014
PubMed
Summary
This summary is machine-generated.

This study presents GTIHR, a genetic algorithm for triploid haplotype reconstruction. The method efficiently reconstructs haplotypes with a higher success rate than existing approaches.

Keywords:
Single nucleotide polymorphism (SNP)Triploidgenetic algorithmhaplotypethe minimum error correction

More Related Videos

Manipulation of Ploidy in Caenorhabditis elegans
07:54

Manipulation of Ploidy in Caenorhabditis elegans

Published on: March 15, 2018

12.1K
Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
06:18

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

918

Related Experiment Videos

Last Updated: Apr 23, 2026

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
11:54

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Published on: October 20, 2019

8.3K
Manipulation of Ploidy in Caenorhabditis elegans
07:54

Manipulation of Ploidy in Caenorhabditis elegans

Published on: March 15, 2018

12.1K
Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
06:18

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

918

Area of Science:

  • Genetics
  • Bioinformatics
  • Computational Biology

Background:

  • Haplotype reconstruction is crucial for understanding genetic variation.
  • The minimum error correction model is a key combinatorial tool for this task.
  • Reconstructing haplotypes for triploid individuals presents unique challenges.

Purpose of the Study:

  • To address the challenge of triploid individual haplotype reconstruction.
  • To introduce a novel genetic algorithm, GTIHR, for this purpose.
  • To improve the efficiency and accuracy of haplotype reconstruction.

Main Methods:

  • Utilized the minimum error correction model.
  • Developed a genetic algorithm named GTIHR.
  • Introduced a novel, efficient chromosome coding method.
  • Implemented an effective hill-climbing operator to optimize convergence.

Main Results:

  • The GTIHR algorithm demonstrated efficient implementation.
  • Achieved a higher haplotype reconstruction rate compared to previous methods.
  • The novel coding and hill-climbing operator contributed to faster convergence and better solutions.

Conclusions:

  • GTIHR is an effective and efficient method for triploid haplotype reconstruction.
  • The algorithm offers improved accuracy and speed.
  • This work advances computational methods in genetic analysis.