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Related Experiment Video

Updated: Apr 23, 2026

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants
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Regulating the placebo effect in clinical practice.

Tracey E Chan1

  • 1Faculty of Law, National University of Singapore, 469G Bukit Timah Road, Eu Tong Sen Building, Singapore 259776 lawchant@nus.edu.sg.

Medical Law Review
|September 18, 2014
PubMed
Summary
This summary is machine-generated.

This study reappraises the clinical and ethical use of placebos, arguing they can be ethically justified without violating patient trust or autonomy. New regulatory oversight is recommended for placebo use in healthcare.

Keywords:
Deceptioninformed consentplacebo effectregulation of innovative treatmenttherapeutic privilege

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Area of Science:

  • Medical Ethics
  • Clinical Practice
  • Health Law

Background:

  • The use of placebos in medicine faces ethical scrutiny due to concerns about deception.
  • Deception in healthcare can undermine patient autonomy and the physician-patient relationship.

Purpose of the Study:

  • To review nuanced scientific understandings of the placebo effect.
  • To evaluate ethical and legal objections to placebo use in clinical settings.
  • To propose a framework for the ethical accommodation of placebos.

Main Methods:

  • Review of recent research on placebo effects.
  • Ethical and legal analysis of placebo deployment.
  • Reconceptualization of the placebo effect in clinical contexts.

Main Results:

  • The placebo effect may be ethically accommodated without requiring material disclosures.
  • Therapeutic privilege can justify the use of placebos in certain clinical situations.
  • A reconceptualization of placebos offers new justification for therapeutic privilege.

Conclusions:

  • Placebo use can be ethically reconciled with patient autonomy and trust.
  • Therapeutic privilege provides a legal and ethical basis for placebo administration.
  • Special regulatory supervision is necessary for the clinical use of placebos.