Maternal and perinatal predictors of newborn iron status

Susan B Morton, Rajneeta Saraf, Dinusha K Bandara

  • 1Growing Up in New Zealand, Centre for Longitudinal Research - He Ara ki Mua, University of Auckland, 261 Morrin Road, Glen Innes, PO Box 18288, Auckland 1743, New Zealand. cc.grant@auckland.ac.nz.

Insights

Seven percent of newborns in New Zealand show iron deficiency at birth. Maternal milk consumption during pregnancy was linked to lower infant serum ferritin levels.

Area of Science:

  • Neonatal Health
  • Nutritional Biochemistry

Background:

  • Iron deficiency at birth can impact infant development and long-term health outcomes.
  • Understanding iron status in newborns is crucial for public health initiatives.

Purpose of the Study:

  • To determine the prevalence of iron deficiency in a New Zealand infant population at birth.
  • To investigate associations between cord blood iron status markers and maternal/birth characteristics.

Main Methods:

  • Cord blood samples were collected from 131 infants in the Growing Up in New Zealand cohort study.
  • Serum ferritin (SF) and haemoglobin (Hb) concentrations were measured.
  • Statistical analyses explored relationships between SF/Hb and maternal/birth factors.

Main Results:

  • Seven percent of newborns exhibited low cord serum ferritin (SF <35 mcg/L), indicating iron deficiency.
  • Two newborns were anaemic (Hb <130 g/L); none had iron deficiency anaemia.
  • Higher maternal milk intake (≥3 servings/day) was associated with lower median SF levels in newborns (131 vs. 151 mcg/L, P=0.04).

Conclusions:

  • Iron deficiency is a notable concern in 7% of New Zealand newborns.
  • Maternal milk consumption during pregnancy may be inversely associated with newborn iron stores.
Abstract

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