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Klippel-Trenaunay syndrome and gestational trophoblastic neoplasm
Priya Sreenivasan1, Sobha Kumar, K K Santhosh Kumar
1Department of Pediatrics, Government Medical College, Thiruvananthapuram, Kerala. Correspondence to: Dr Priya Sreenivasan, Assistant Professor of Pediatrics, Government Medical College, Thiruvananthapuram, Kerala. priyavineed@yahoo.co.in.
Background:
Klippel-Trenaunay syndrome is a non-heritable venous malformation with bone and soft tissue hypertrophy and cutaneous nevi.
Case Characteristics:
Neonate with Klippel Trenaunay syndrome born to a mother with past history of Gestational trophoblastic neoplasm.
Observation:
Antenatally, a fetal vascular malformation was identified ultrasonologically at 29 weeks gestation. Acute myeloid leukemia was diagnosed in mother at 33 weeks gestation.
Message:
A rare association of Klippel Trenaunay syndrome and gestational trophoblastic neoplasm with the possible role of either hyperglycosylated Human Chorionic Gonadotropin or chemotherapy as a link is highlighted.
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