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Sensitive and selective amplified visual detection of cytokines based on exonuclease III-aided target recycling
Kai Zhang1, Tianli Ren, Ke Wang
1Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine. Wuxi, Jiangsu 214063, China. zhangkai@jsinm.org xieminhao@jsinm.org.
Chemical Communications (Cambridge, England)
|September 19, 2014
Abstract:
A new Exo III assisted strand-cleavage cycle and ligand-responsive quadruplex formation strategy for amplified and label-free detection of IFN-γ was reported with a detection limit of 0.1 pM and a visual detection limit of 20 pM by the naked eye.
