Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alpha hydroxy acids: procedures for use in clinical practice.

E J Van Scott1, R J Yu

  • 1Department of Dermatology, Temple University School of Medicine, Philadelphia, Pennsylvania.

Cutis
|March 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[A case of allergy to isoproterenol injection during cardiac radiofrequency ablation].

Zhonghua xin xue guan bing za zhi·2025
Same author

[Diatoms Distribution in Ningbo Three-river Watershed during Summer].

Fa yi xue za zhi·2017
Same author

[Sturge-Weber syndrome in port-wine stain patients: a retrospective study on the clinical features and screening strategy].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2017
Same author

[The study of quantitative evaluation between age and dyspnea in the healthy].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology·2010
Same author

Objective bioengineering methods to assess the effects of moisturizers on xerotic leg skin of elderly people.

The Journal of dermatological treatment·2002
Same author

[Effects of smoking on the lipid peroxides antioxidation and alpha 1-antitrypsin].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2001
Same journal

Black Dots on the Scalp of a Child.

Cutis·2026
Same journal

Psoriasis and Obesity: A Clinical Review of the Bidirectional Link and Management Implications.

Cutis·2026
Same journal

Adalimumab in Lichen Planus: A Narrative Review of Treatment and Paradoxical Reactions.

Cutis·2026
Same journal

The Future of Psoriasis Care.

Cutis·2026
Same journal

Evaluating GPT-4o for Automated Classification of Skin Lesions Using the HAM10000 Dataset.

Cutis·2026
Same journal

Metastatic Primary Extramammary Paget Disease: A Case Series.

Cutis·2026
See all related articles

Alpha hydroxy acids (AHAs) and alpha keto acids (AKAs) effectively treat skin conditions. Lower concentrations manage dry skin and hyperkeratosis, while higher concentrations offer new options for keratoses and wrinkles.

Area of Science:

  • Dermatology
  • Cosmetic Science

Background:

  • Hyperkeratotic stratum corneum and epidermal hyperplasia characterize various skin conditions.
  • Alpha hydroxy acids (AHAs) and alpha keto acids (AKAs) have demonstrated therapeutic potential.

Purpose of the Study:

  • To elucidate the mechanisms by which AHAs and AKAs affect the stratum corneum.
  • To explore the clinical applications of AHAs and AKAs in treating dermatological conditions and improving skin appearance.

Main Methods:

  • Topical application of AHAs and AKAs at varying concentrations.
  • Clinical observation and assessment of treatment outcomes for various skin conditions.

Main Results:

  • Lower concentrations of AHAs/AKAs reduce stratum corneum thickness by decreasing corneocyte cohesion, aiding in the management of dry skin, ichthyosis, and follicular hyperkeratosis.

Related Experiment Videos

  • Higher concentrations induce epidermolysis, providing a novel treatment for seborrheic keratoses, actinic keratoses, verrucae vulgares, and age spots.
  • Combined high-concentration office procedures and low-concentration daily home applications of AHAs can modify facial wrinkles.

    • Conclusions:

    • AHAs and AKAs offer versatile therapeutic options for a range of dermatological concerns.
    • Concentration-dependent effects of AHAs and AKAs allow for tailored treatment strategies.
    • These acids represent a significant advancement in managing hyperkeratotic disorders and improving aesthetic concerns like wrinkles.