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Beyond the connectome: the dynome.

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The human connectome maps brain connections, but understanding function requires integrating connectivity with dynamics and biology. This perspective introduces the "dynome" framework to link brain dynamics to cognition.

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Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Systems Neuroscience

Background:

  • The human connectome project aims to map neural connections, offering insights into brain health and disease.
  • Current understanding of brain function and dysfunction is limited by a lack of integrated frameworks linking connectivity, dynamics, and biological underpinnings.

Purpose of the Study:

  • To propose an integrated framework, termed the

Main Methods:

  • Conceptual framework development
  • Literature review and synthesis

Main Results:

  • The proposed

Conclusions:

  • An integrated framework is essential for advancing our understanding of brain function and dysfunction.
  • The