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Internal jugular vein thrombosis complicating disseminated tuberculosis in a 2-year-old child
Sarthak Das1, Rangan Srinivasaraghavan1, Sriram Krishnamurthy1
1Department of Paediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India.
Insights
Internal jugular vein thrombosis in children, often linked to cancer or infections, can now be associated with tuberculosis. Early diagnosis and treatment with antitubercular drugs and warfarin led to full recovery in a pediatric case.
Area of Science:
- Pediatric Medicine
- Vascular Thrombosis
- Infectious Diseases
Background:
- Internal jugular vein (IJV) thrombosis is a critical pediatric condition.
- Commonly associated with malignancies, central venous catheters, infections, or trauma.
- No prior cases linked IJV thrombosis to tuberculosis in children.
Observation:
- A 2-year-old child presented with IJV thrombosis.
- The child exhibited clinical signs of disseminated tuberculosis.
- The case highlights a novel association between IJV thrombosis and pediatric tuberculosis.
Findings:
- Complete resolution of IJV thrombosis symptoms occurred.
- Treatment involved antitubercular drugs and warfarin.
- This suggests a potential link between tuberculosis and IJV thrombosis.
Implications:
- Recommends routine tuberculosis screening for pediatric IJV thrombosis.
- Suggests considering tuberculosis in cases with mediastinal mass or lymphadenopathy.
- Broadens the differential diagnosis for pediatric IJV thrombosis.
Abstract:
Internal jugular vein (IJV) thrombosis is a serious and potentially life-threatening occurrence in children, and is usually associated with malignancies, prolonged central venous catheterisation or deep seated head and neck infections or trauma. It has not been described in association with tuberculosis in children. The authors describe a 2-year-old child who presented with IJV thrombosis in association with clinical signs and symptoms of disseminated tuberculosis. There was complete resolution of symptoms after starting antitubercular drugs and warfarin. The authors emphasise that an active search for tuberculosis should be made routinely in patients with IJV thrombosis with an underlying mediastinal mass and/or generalised lymphadenopathy.
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