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Updated: Apr 23, 2026
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Real-Time Void Spot Assay
Published on: February 10, 2023
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The Nocturia Impact Diary: a self-reported impact measure to complement the voiding diary.
Tove Holm-Larsen1, Fredrik Andersson2, Egbert van der Meulen3
1Pharma Evidence, Farum, Denmark; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Summary
The new Nocturia Impact Diary effectively measures nocturia's effects on quality of life. This validated tool aids in assessing treatment outcomes for nocturia patients.
Area of Science:
- Urology
- Patient-Reported Outcome Measures
- Psychometrics
Background:
- Nocturia significantly disrupts sleep and impacts patient quality of life.
- Current tools for assessing nocturia's impact are suboptimal.
- Validated measures are crucial for evaluating nocturia treatments.
Purpose of the Study:
- Develop and validate the Nocturia Impact Diary (NID).
- Augment the Nocturia Quality of Life questionnaire.
- Integrate with the standard 3-day voiding diary.
Main Methods:
- Concept pool development using existing questionnaires and studies.
- Content validity assessment through cognitive debriefing with patients.
- Psychometric validation including construct validity, reliability, and sensitivity in a clinical trial.
Main Results:
- The diary, with 14 items across 4 domains, showed high content validity.
- Psychometric testing confirmed high construct validity, reliability, and sensitivity to change.
- The Nocturia Impact Diary demonstrated unidimensionality and good fit to the Rasch model.
Conclusions:
- The Nocturia Impact Diary is a validated and convenient patient-reported outcome measure.
- It effectively captures the real-life consequences of nocturia.
- Recommended for use alongside voiding diaries to assess nocturia and its treatment impact.
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