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Updated: Apr 23, 2026

'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens
Published on: July 8, 2011
Plague's partners in crime
Kimberly M Davis1, Ralph R Isberg1
1Howard Hughes Medical Institute, Tufts University School of Medicine, 150 Harrison Avenue, Boston, MA 02111, USA; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 150 Harrison Avenue, Boston, MA 02111, USA.
Abstract:
The hallmark of bubonic plague is the presence of grotesquely swollen lymph nodes, called buboes. This frenzied inflammatory response to Yersinia pestis is poorly understood. In this issue of Immunity, St. John et al. (2014) explore the mechanism by which Y. pestis spreads and thus leads to this striking lymphadenopathy.
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