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Published on: January 13, 2017
Structure elucidation and cytotoxic evaluation of new polyacetylenes from a marine sponge Petrosia sp
Yung-Shun Juan1, Chien-Chih Lee2, Chia-Wei Tsao3
1Department of Urology, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung 812, Taiwan. juanuro@gmail.com.
Abstract:
The sponge Petrosia sp. yielded five polyacetylenic compounds (1-5), including two new polyacetylenes, petrosianynes A (1) and B (2). The structures of these compounds were elucidated by detailed spectroscopic analysis and by comparison with the physical and spectral data of related known analogues. Compounds 1-5 exhibited significant cytotoxic activity against a limited panel of cancer cell lines.
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