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Updated: Apr 23, 2026

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
Published on: December 15, 2023
Association between exposure to hepatitis B virus and chronic kidney disease in China
Qiang Zeng1, Yan Gong2, Shengyong Dong2
1International Medical Centre, Chinese PLA General Hospital, Beijing, China qiangzeng123@yeah.net.
Objective:
Hospital-based, cross-sectional study to determine whether exposure to hepatitis B virus (HBV) has an independent effect on the risk of developing chronic kidney disease (CKD).
Methods:
Han Chinese adults undergoing routine physical examinations were recruited. Blood was tested for the presence of hepatitis C virus (HCV) antibodies, HBV surface antigen, and antibodies against HBV core antigen and hepatitis B surface antigen (HBsAg). CKD was defined as estimated glomerular filtration rate (eGFR) <60 ml/min per 1.73 m(2) or presence of albuminuria.
Results:
The prevalence of HBV exposure was 42.1% (6,418/15,259 participants). There were no significant associations between HBV or HCV status and CKD, low eGFR or albuminuria.
Conclusion:
There was no association between exposure to HBV and the risk of developing CKD in this Chinese study population.
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