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Published on: January 17, 2018
[Clinical analysis of sinonasal hemangiopericytoma]
Qingjia Gu1, Gang Xu, Gang He2
1Department of Otorhinolaryngology, Sichuan Provincial People's Hospital, Chengdu 610072, China.
Insights
Sinonasal hemangiopericytoma is rare. Endoscopic or endoscope-assisted surgery offers a satisfactory treatment effect for this sinonasal tumor, with most patients showing no recurrence after treatment.
Area of Science:
- Oncology
- Otorhinolaryngology
Context:
- Sinonasal hemangiopericytoma is a rare tumor.
- Diagnosis relies on pathology and immunohistochemistry.
Purpose:
- To investigate the clinical features, therapeutic methods, and effects of sinonasal hemangiopericytoma.
- To evaluate surgical outcomes for this rare sinonasal tumor.
Summary:
- Retrospective analysis of 6 patients (4 male, 2 female, median age 58) with sinonasal hemangiopericytoma.
- Clinical features included epistaxis and nasal obstruction.
- Nasal endoscopic or endoscope-assisted surgery was performed; 2 recurrences were observed during follow-up (6 months to 7 years).
Impact:
- Nasal endoscopic surgery provides a satisfactory therapeutic effect for sinonasal hemangiopericytoma.
- Highlights the importance of surgical intervention for rare sinonasal tumors.
Objective:
To investigate the clinical features, therapeutic methods and therapeutic effects of sinonasal hemangiopericytoma.
Methods:
Clinical data of 6 patients with sinonasal hemangiopericytoma, diagnosed by pathology and immunohistochemistry between January 1990 and December 2012 were analyzed retrospectively. There were 4 males and 2 females, with a median age of 58 years. Clinical manifestation included epistaxis and nasal obstruction. These patients were operated on by nasal endoscopic surgery or endoscope-assisted surgery, of which 2 cases of tumor located in the nasal cavity underwent nasal endoscopic surgery and 4 cases of tumor located in the nasal cavity and sinuses underwent endoscope-assisted surgery.
Results:
All the patients were followed up for a period of 6 months to 7 years after operation. Two cases recurred and 4 cases didn't recurred. One case recurred 6 months after operation and underwent second operation, with no recurrence by further one year follow-up. Another case recurred 17 months after operation and underwent second operation, with recurrence by further 9 months follow-up. This patient lived with tumor over two years.
Conclusions:
Hemangiopericytomas are rarely found in the sinonasal cavity. Nasal endoscopic or endoscope-assisted surgery provides satisfactory effect.
