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Published on: December 6, 2016
[Treatment of obstructive sleep apnea-hypopnea syndrome for children refractory asthma]
Yingxia Lu1, Qinglong Gu2, Chong Pang
1Department of Otorhinolaryngology, Capital Institute of Pediatrics affiliated Children's hospital, Beijing 100020, China.
Insights
Treating obstructive sleep apnea-hypopnea syndrome (OSAHS) in children with refractory asthma improves symptoms. Surgical intervention for OSAHS offers superior outcomes compared to conservative methods, enhancing asthma control.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Asthma Research
Context:
- Refractory asthma in children often co-exists with obstructive sleep apnea-hypopnea syndrome (OSAHS).
- OSAHS can exacerbate asthma control, posing a challenge for effective management.
- Understanding the impact of OSAHS treatment on pediatric asthma is crucial.
Purpose:
- To evaluate the effectiveness of different treatments for OSAHS in children with refractory asthma.
- To compare surgical versus conservative OSAHS treatment outcomes in this patient population.
Summary:
- This study assessed 52 children with refractory asthma and OSAHS, comparing surgical and conservative OSAHS treatments over 6 months.
- Both treatment groups showed improved polysomnography (PSG) values and asthma control, with surgical intervention yielding significantly better results.
- Surgical treatment demonstrated a higher cure rate and greater improvement in asthma parameters and reduced medication use compared to conservative methods.
Impact:
- Active OSAHS management, particularly surgical treatment, significantly improves asthma control and reduces medication reliance in children.
- Findings highlight the importance of addressing OSAHS as a key factor in managing refractory pediatric asthma.
- This research provides evidence supporting surgical intervention for OSAHS in refractory pediatric asthma cases.
Objective:
The aim of this study was to understand the effect of different treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) for refractory asthma in children.
Methods:
Fifty two children (32 in surgical group, 20 in conservative group) with refractory asthma and OSAHS were included in the study. All children received asthma condition assessment and polysomnography (PSG) examination before and after treatment, and were followed up for 6 months.
Results:
All children got improved in PSG values 3 months after treatment, more significant improvement was achieved in surgical group than in conservative group (P < 0.05). While compared of OSAHS treatment, there were 2 cure, 6 notable effective, 9 effective, 3 in vain cases in conservative group, 8 cure, 16 notable effective, 8 effective, 0 in vain cases in surgery group. There was significant difference between the two groups (χ² = 8.91, P = 0.031). All children got improved in asthma condition evaluation parameters and decreased the use number of short acting β2 agonists after 6 months treatment. More significant improvement was achieved in surgical group than in conservative group. The differences of all the items had statistical significance (P < 0.05). There was statistical correlation between days mutation rate of peak expiratory flow (PEF) and apnea hypopnea index (r = 0.712, P < 0.01), and between days mutation rate of PEF and lowest oxygen saturation (r = 0.726, P < 0.01).
Conclusions:
Active treatment of OSAHS can improve asthma symptoms and reduce asthma medication effectively. The curative effect of surgical treatment is superior to conservative treatment.
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