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Updated: Apr 23, 2026

Measuring Microbial Mutation Rates with the Fluctuation Assay
Published on: November 28, 2019
The basic science and mathematics of random mutation and natural selection
1PO Box 1240, Coarsegold, 93614, CA, U.S.A.
Abstract:
The mutation and natural selection phenomenon can and often does cause the failure of antimicrobial, herbicidal, pesticide and cancer treatments selection pressures. This phenomenon operates in a mathematically predictable behavior, which when understood leads to approaches to reduce and prevent the failure of the use of these selection pressures. The mathematical behavior of mutation and selection is derived using the principles given by probability theory. The derivation of the equations describing the mutation and selection phenomenon is carried out in the context of an empirical example.
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