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Updated: Apr 23, 2026

Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System
Published on: January 5, 2024
Carbapenem resistance in a human clinical isolate identified to be closely related to Acinetobacter indicus
Rémy A Bonnin1, Laurent Poirel2, Tanny J K van der Reijden3
1INSERM U914 'Emerging Resistance to Antibiotics', K.-Bicêtre, France.
Abstract:
Here we report a case of carbapenem resistance in a human clinical isolate that was found to be closely related to the newly described environmental species Acinetobacter indicus. This strain harboured the blaOXA-23 carbapenemase gene located on a conjugative plasmid. Partial sequencing of 16S rDNA and rpoB genes, together with matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) analysis, showed that this strain was distantly related to the Acinetobacter baumannii-calcoaceticus complex and was closely related to A. indicus.
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