Related Experiment Video
Updated: Apr 23, 2026
09:04
Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
Published on: March 7, 2025
1.8K
Cancer immunoprevention--the next frontier
Marie-Anne D Smit1, Elizabeth M Jaffee2, Eric R Lutz3
1The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Cancer Prevention Research (Philadelphia, Pa.)
|September 24, 2014
Summary
Cancer immunoprevention offers a promising strategy to prevent cancer before immune tolerance develops and to combat recurrence. Research is advancing, particularly in secondary prevention after adjuvant therapy.
Area of Science:
- Oncology
- Immunology
- Preventive Medicine
Background:
- Cancer immunotherapy faces challenges with high tumor burden and immune tolerance.
- Immunoprevention can overcome immune tolerance and address minimal residual disease.
- Viral-induced cancer immunoprevention (e.g., Hepatitis B, HPV) is established, but primary prevention for non-viral cancers is nascent.
Purpose of the Study:
- To review recent advancements in cancer immunoprevention research.
- To explore future research directions in the field of cancer immunoprevention.
Main Methods:
- Literature review of cancer immunoprevention studies from the past three years.
- Analysis of current trends and emerging strategies in cancer immunoprevention.
Main Results:
- Significant progress in understanding immune tolerance in cancer.
- Growing momentum in secondary cancer prevention strategies.
- Identification of key areas for future research in primary and secondary immunoprevention.
Conclusions:
- Cancer immunoprevention holds significant potential, especially for preventing recurrence.
- Further research is crucial to advance primary prevention for non-viral cancers.
- The field is evolving, with a focus on overcoming current therapeutic limitations.
Related Concept Videos
01:27Tumor Immunotherapy
2.5K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.5K
01:30Cancer Vaccines
1.3K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.3K
02:59Cancer Prevention
6.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.5K
02:59Cancer Prevention
2.6K
2.6K
02:49Cancer Therapies
7.9K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.9K
02:49Cancer Therapies
2.4K
2.4K