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Triptan use in Italy: Insights from administrative databases
Roberto Da Cas1, Anna Nigro2, Salvatore Terrazzino3
1National Centre for Epidemiology, Surveillance and Health Promotion, National Institute of Health, Italy.
Cephalalgia : an International Journal of Headache
|September 24, 2014
Summary
Approximately 10% of Italian triptan users may be at risk for medication-overuse headache (MOH). Prescription databases can help identify these patients for targeted interventions.
Area of Science:
- Pharmacovigilance
- Neurology
- Public Health
Background:
- Assesses triptan utilization patterns in Italy.
- Utilizes drug prescription databases covering approximately 1 million citizens.
Purpose of the Study:
- To evaluate the pattern of triptan use in the Italian population.
- To identify individuals potentially at risk for medication-overuse headache (MOH).
Main Methods:
- Included residents aged 18-84 from Vercelli and Umbria regions with triptan dispensations in 2012.
- Defined frequent users as those with ≥10 defined daily doses (DDD) monthly for ≥3 consecutive months.
- Analyzed prescription data to determine triptan usage frequency and risk factors.
Main Results:
- Triptan use ranged from 0.7%-1% of the population.
- Approximately 10% of triptan users were classified as frequent users.
- Frequent users were most common in the 40-49 age group, with no sex difference; persistence of frequent use was observed.
Conclusions:
- About 10% of Italian triptan users are potentially at risk for MOH.
- Drug prescription databases offer a viable method for identifying patients at risk of MOH.
- This approach can inform targeted interventions for headache management.
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