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Epidemiological aspects of pertussis among adults and adolescents in a Korean outpatient setting: a multicenter,

Sunghoon Park1, Sun Hwa Lee2, Ki-Hyun Seo3

  • 1Division of Pulmonary, Allergy and Critical Care Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea.

Journal of Korean Medical Science
|September 24, 2014
PubMed

Insights

Pertussis (whooping cough) affects 6.9% of adolescents and adults with acute cough in Korea. Secondary referral hospitals and seasonal peaks in February and August showed higher pertussis incidence.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Microbiology

Background:

  • Limited epidemiological data exists for Bordetella pertussis infections in Korean adolescents and adults.
  • Pertussis, or whooping cough, remains a concern in various age groups.

Purpose of the Study:

  • To determine the prevalence of pertussis in adolescents and adults presenting with acute cough in Korea.
  • To identify epidemiological factors associated with pertussis in this population.

Main Methods:

  • A prospective study enrolled 490 patients (age ≥ 11 years) with cough < 30 days at 22 Korean hospitals.
  • Nasopharyngeal swabs were analyzed using polymerase chain reaction (PCR) and bacteriologic culture for B. pertussis detection.
  • Statistical analysis included multivariate analysis to identify associated factors.

Main Results:

  • Bordetella pertussis was confirmed in 34 (6.9%) patients.
  • Higher incidence was observed in secondary referral hospitals (10.6%) compared to primary (3.4%) or tertiary (4.0%) facilities.
  • Peak incidence occurred in February and August, with post-tussive vomiting significantly associated with pertussis.

Conclusions:

  • Pertussis is present in 6.9% of Korean adolescents and adults with acute cough in outpatient settings.
  • Hospital level and seasonal variations influence pertussis incidence, requiring tailored control strategies.
  • PCR-based detection is effective for diagnosing pertussis in this demographic.

Keywords:
AdultHospitalsIncidencePertussisSeasons

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